What is Cellosis?
(April 2, 2010; updated January 13, 2011,
December 13, 2011)
(also known as "type 2 diabetes"
and "adult onset diabetes", as well as
* Pancreas able to produce insulin, but in an
insufficient amount to overcome cells' insulin
resistance - in about 25% of Americans with
Cellosis, insulin must be injected or, in rare
cases, pumped as part of the treatment regi-
men which also includes diet, exercise, and
in many cases, oral medication
Cellosis Overview / Description
The Cell being referred to is the small mass of protoplasm
bounded by semipermeable membrane, capable of per-
forming fundamental functions of life.
osis part of the new word :
a suffix occurring in nouns that denote actions, conditions,
or states, esp. disorders or abnormal states.
In persons with Cellosis, the body's cells do not respond
correctly to Insulin. This is called Insulin Resistance. Insulin
Resistance means that fat, liver, and muscle cells do not
respond normally to Insulin. As a result blood sugar does
not get into cells to be stored for energy as it did prior to
the onset of Cellosis.
Cellosis typically starts out with Insulin Resistance, and
persons impacted initially produce Insulin in proper
amounts, it's just that the cells' ability to use the Insulin
to produce energy begins to be resisted. If the disease
continues without steps to decrease the Insulin Resistance
through diet, exercise, and/or medications, a persons'
ability to produce enough Insulin will diminish, their
glucose levels will rise, and over time, if undiagnosed
and/or if adequate counter measures aren't taken, serious
medical consequences will occur.
Treatments for Persons With Cellosis
Some of the most common types of medication to address
Cellosis are listed below. Note -- None of these medica-
tions can be used to address Insulinitis.
Biguanides (Metformin) tell the liver to produce less
glucose and help muscle and fat cells and the liver
absorb more glucose from the bloodstream. This
lowers blood sugar levels.
Sulfonylureas (like glimepiride, glyburide, and tolaza-
mide) trigger the pancreas to make more insulin. They
are taken by mouth.
Thiazolidinediones (such as rosiglitazone) help muscle
and fat cells and the liver absorb more blood sugar when
insulin is present. Rosiglitazone may increase the risk
of heart problems. Talk to your doctor.
Injectible medications (including exenatide and pramlin-
tide) can lower blood sugar.
Meglitinides (including repaglinide and nateglinide) trigger
the pancreas to make more insulin in response to the
level of glucose in the blood.
Alpha-glucosidase inhibitors (such as acarbose) decrease
the absorption of carbohydrates from the digestive tract
to lower after-meal glucose levels.
If Cellosis isn't countered by diet, exercise, or any of the
medications listed above (or by other medications, or by
surgery - see below), to reduce the chances of medical
complications, Insulin must be injected to supplement the
Insulin which persons with Cellosis continue to automatic-
ally release. Insulin cannot be taken by mouth (not yet,
anyway, though research into both inhaled -and- oral
Insulin is in development, and if developed, would be
available to persons with Insulinitis and to persons with
- - -
Summary - Insulinitis compared to Cellosis
Age of Onset:
Typically, Insulinitis occurs
to children, although it can
occur to babies and adults. I got
Insulinitis when I was
5 years old.
Typically, Cellosis occurs to
adults, although it can
occur to children.
Insulinitis is genetically
caused, with the pancreas
stopping the production of Insulin.
Cellosis may entail genetic
and/or lifestyle and/or age
causality, with risks increasing as
persons gain weight
and as they age, with cells resisting the
continues to be automatically produced in persons
Insulinitis requires injection
with Insulin (most often
multiple times per day - I typically
take 6 shots per
day, though sometimes I only take 4 or 5,
on bedtime glucose level) or delivery via a pump.
Cellosis is dealt with by
diet, exercise, and medica-
tions which cannot be used by persons with
If those methods fail, Insulin must also be
supplement the Insulin which persons with Cellosis
continue to automatically release.
Insulinitis currently has no
cure. Methods being
researched include a closed loop
a pancreas transplant, an islet cell
cell research, leptin, and other areas.
Cellosis can go into remission
in some cases, with
diet, exercise, medications, and the
also be in play when the condition is
Excerpt: ... 83% of patients
experience a complete
remission of type 2 diabetes
after gastric bypass