Artificial Pancreas --  Coming Soon?
Type 1 Diabetes 'Cure'?
(Top Posts - Science - 040109)

Artificial Pancreas Project at the
University of Virginia

Continuous glucose monitors
and artificial pancreas

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August 2008

Researchers Outline Steps to
Artificial Pancreas
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Artificial Pancreas -- JDRF Website
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JDRF's CGM Research Named One of Top 10
Medical Breakthroughs of 2008

ABC News Lists Human Clinical Trial of
Continuous Glucose Monitors Among Year's
Most Important Advancements

Leslie Schwartz, National Director, Media Relations
Ph: 212-479-7553
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New York, NY, January 8, 2009 -- The ground-
breaking human clinical trial funded by JDRF
that showed that continuous glucose monitors
can improve diabetes control was cited by the
ABC television network as one of the top 10
medical breakthroughs of 2008.


The JDRF CGM trial was the first major, multi-
center trial to document the benefits of CGM
devices in helping people with type 1 diabetes
better control blood sugar levels and reduce
the risk of devastating complications.

CGM devices, manufactured by several com-
panies and approved by the FDA as an adjunc-
tive therapeutic for diabetes, are a small mon-
itor connected to a sensor that people with
diabetes wear, that provide both a real-time
snapshot of the glucose levels of a person
with diabetes, as well as trend information on
whether glucose is moving upwards or down-
wards, and how fast.

The devices also provide warnings when the
glucose is becoming too high or too low - both
dangerous conditions.


"These study results promise to be a corner-
stone of our research into metabolic control
and the development of an artificial pancreas,
as it shows that these technologies can pro-
vide significant improvements in the lives of
people with diabetes."


The JDRF study was a randomized, controlled
trial involving 322 patients spanning the age range
of 8 to 72 years at 10 sites ...

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October 10, 2008

Artificial Pancreas Could Revolutionize
Treatment of Type 1 Diabetes
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U.Va. investigators have completed the first of
several international artificial pancreas clinical
trials to test an individually-"prescribed" con-
trol algorithm, which regulates blood glucose
levels in Type 1 diabetics.


"This artificial pancreas could one day greatly
improve the current methods of self-treatment for
Type 1 diabetes," Kovatchev said. "Instead of a
patient having to measure his or her blood sugar
with a glucose meter several times a day and self-
administer insulin injections, this system would
continuously regulate the patient's blood glucose,
much like the way a non-diabetic's pancreas func-


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Sure looks like a 'cure' for type 1 diabetes
is getting ever so close (103008)
"Ideally, type 1 diabetics, in some form of
a 'cure', would return to the way they were
before they became diabetic, and would be
like non-diabetics -- eating, socializing, work-
ing, and living without worrying about losing
consciousness, giving insulin shots, blood
sugars going too low, blood sugars going
too high, or any of the complications that
can result from having type 1 diabetes. ..."
Mechanical Cure For Type 1 Diabetes?
Could be, and the key word is SOON!
"... Researchers at the University of Cambridge
have just begun clinical trials of an “artificial
pancreas” at Addenbrooke's Hospital. The
“artificial pancreas” can improve control over
the wide fluctuations of a patient's glucose levels
that, over time, lead to severe complications
such as heart attack, stroke, kidney failure,
amputations, blindness and premature death. ..."
Pro-Humanist FREELOVER Daily - 090401
Significant Advance Towards Artificial Liver &

Individuals with liver and pancreatic disorders may
some day be treated and even cured, thanks to a
new method of storing living cells in a device capable
of being attached to the body to do the job of dam-
aged tissue.

Bio-artificial organs could help millions of persons
suffering from liver disorders. A similar device im-
planted into the body could help people with pan-
creatic conditions, such as diabetes and perhaps
replace daily insulin injections.

Dr Helen Grant has developed a method of freezing
liver cells at -70C in single layers attached to a mem-
brane, providing a ready source of tissue for artificial
organs. This is a significant advance in the ability to
use bio-artificial organs in place of damaged tissue.



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