Type 1 Diabetes Cure, DiabeCell®?
(Top Posts - Science - 102207)

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Early trial results are promising.

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October 22, 2007

Sydney Morning Herald
  http://tinyurl.com/24y7fk
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Excerpts:

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[Cell therapy company Living Cell Technologies Ltd]
medical director Professor Bob Elliott said early
stage results of the product, DiabeCell, "have ex-
ceeded our expectations".

Prof Elliott said the first patient was injected with his
first dose of DiabeCell in June without adverse ef-
fects, resulting in the patient's insulin requirement
being reduced.

"Control of blood glucose levels has been maintained
while his daily insulin requirement was gradually
reduced by about 40 per cent over the past four
months," Prof Elliott said.

Prof Elliott said the second recipient was implanted
with her first dose of DiabeCell last month without
adverse effects.

"At one month following the implant, the patient has
been weaned off insulin altogether," he said.

...

Living Cell is trialling DiabeCell on six patients at
the Sklifosovsky Institute in Moscow, Russia.

Patients each receive two transplants of small doses
of live micro-encapsulated pig islets that are injected
into their abdominal.

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Breakthrough In Diabetes Treatment
  http://tinyurl.com/qwrlm4   
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Excerpts:

...

DiabeCell® is a treatment for insulin-dependent dia-
betes which is administered to patients without the
need for immunosuppressant drugs.

The trial in Russia will determine whether a small
dose of live microencapsulated pig islets injected
into the abdominal cavity of type I diabetic patients
is safe and can produce enough insulin to have a
measurable effect on improving the control of blood
glucose levels.

Medical Director of Living Cell, Professor Bob
Elliott, said two patients have been implanted with
their first dose of DiabeCell® and are due for a
second dose in 6 months.

...

Six more patients will be receiving two transplants
of the smallest dose of DiabeCell® which is equiva-
lent to one third of the maximum dose.

A trial of maximum dose transplants is planned for
testing in a proposed New Zealand study.

...

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